Faculty Research

Faculty Research

 

Faculty Members
All MSD professors share a teaching philosophy based on academic rigor, integrity, departmental and institutional mission. We all consider teaching our main profession, and we enjoy being in class with our students. What we value most is academic freedom, small classes that help help us to know our students, and straightforward communication about everything we do. Please feel free to contact any of us if you have any questions about classes, your career, or research.

Bert Coltman - Anatomy, Physiology, Neuroscience
Jeanette Eggert - Math, Physics
Michael Godsey - Biochemistry
Kaycee Gillespie - Assistant Director
Rici Hallstrand - Biology, Immunology
Mihail Iordanov - Microbiology, Molecular Biology, Genetics
Andrew Johnson - Organic Chemistry
Charles Kunert - Genetics
Sergei A. Polozov - Ecology, Ornithology
Julie Rowland - Math
Tom Shuell - Math
Matthew Wise - Analytical Chemistry

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Submissions from 2016

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The Sampling of Conformational Dynamics in Ambient-Temperature Crystal Structures of Arginine Kinase, Michael H. Godsey, Omar Davulcu, Jay C. Nix, Jack J. Skalicky, Rafael P. Brüschweiler, and Michael S. Chapman

Submissions from 2015

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Determination of Total Peroxide Content in Secondary Organic Aerosol Particles, Matthew E. Wise, John Shilling, and Ryan Caylor

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Determination of the Optical Properties of Secondary Organic Aerosol Particles, Matthew E. Wise, John Shilling, Felisha Imholt, and Ryan Caylor

Submissions from 2014

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Effect of 1,3-adamantane Bridging Units Within the Surrounding Macrocyle of Squaraine Rotaxanes, Carleton G. Collins, Andrew T. Johnson, Richard D. Connell, Ruth A. Nelson, Ivan Murqu, Allen G. Oliver, and Bradley D. Smith

Submissions from 2013

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State Transformations and Ice Nucleation in Amorphous (Semi-) Solid Organic Aerosol, K. J. Baustian, M. E. Wise, E. J. Jensen, G. P. Schill, M. A. Freedman, and M. A. Tolbert

Submissions from 2012

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Importance of Aerosol Composition, Mixing State and Morphology for Heterogeneous Ice Nucleation: A Combined Field and Laboratory Approach, Kelly J. Baustian, Daniel J. Cziczo, Matthew E. Wise, Kerri A. Pratt, Gourihar Kulkarni, A. Gannet Hallar, and Margaret A. Tolbert

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State Transformations and Ice Nucleation in Glassy or (Semi-) Solid Amorphous Organic Aerosol, K. J. Baustian, M. E. Wise, E. J. Jensen, G. P. Schill, M. A. Freedman, and M. A. Tolbert

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Proximal Giant Neurofilamentous Axonopathy in Mice Genetically Engineered to Resist Calpain and Caspase Cleavage of α-II Spectrin, R. Kassa, V. Monterroso, J. Wentzell, A. L. Ramos, E. Couchi, M. C. Lecomte, M. Iordanov, D. Kretzschmar, G. Nicolas, and D. Tshala-Katumbay

Introduction to Science, Matthew E. Wise

Introduction to Science Online Edition, Matthew E. Wise

Environmental Chemistry II, Matthew E. Wise and Nabilah A. Rontu-Carlon

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Depositional Ice Nucleation onto Hydrated NaCl Particles: A New Mechanism for Ice Formation in the Troposphere, M. E. Wise, K. J. Baustian, T. Koop, M. A. Freedman, E. J. Jensen, and M. A. Tolbert

Submissions from 2011

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An Epidermotypic Model of Interface Dermatitis Reveals Individual Functions of Fas Ligand and Gamma Interferon in Hypergranulosis, Cytoid Body Formation, and Gene Expression, Sherry M. Farley, Lisa J. Wood, and Mihail S. Iordanov

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Laboratory Studies of Perchlorate Phase Transitions: Support for Metastable Aqueous Perchlorate Solutions on Mars, R. V. Gough, V. F. Chevrier, K. J. Baustian, M. E. Wise, and M. A. Tolbert

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On the Structure and Dynamics of Duplex GNA, Andrew T. Johnson, Mark K. Schlegel, Eric Meggers, Lars-Oliver Essen, and Olaf Wiest

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Does the Cycad Genotoxin MAM Implicated in Guam ALS-PDC Induce Disease-Relevant Changes in Mouse Brain that Includes Olfaction?, Glen Kisby, Valerie Palmer, Mike Lasarev, Rebecca Fry, Mihail Iordanov, Eli Magun, Leona Samson, and Peter Spencer

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Doxorubicin and Daunorubicin Induce Processing and Release of Interleukin-1β through Activation of the NLRP3 Inflammasome, Kristin A. D. Sauter, Lisa J. Wood, John Wong, Mihail Iordanov, and Bruce E. Magun

Environmental Chemistry, Matthew Wise

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Depositional Ice Nucleation onto Hydrated NaCl Particles: a New Mechanism for Ice Formation in the Troposphere, M. E. Wise, K. J. Baustian, T. Koop, M. A. Freedman, E. J. Jensen, and M. A. Tolbert

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Incorporation of Porphyrin Acetylides into Duplexes of the Simplified Nucleic Acid GNA, Hui Zhou, Andrew T. Johnson, Olaf Wiest, and Lilu Zhang

Submissions from 2010

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Depositional Ice Nucleation on Solid Ammonium Sulfate and Glutaric Acid Particles, K. J. Baustian, M. E. Wise, and M. A. Tolbert

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Characterizing the Morphology of Organic Aerosols at Ambient Temperature and Pressure, Miriam A. Freedman, Kelly J. Baustian, Matthew E. Wise, and Margaret A. Tolbert

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Evaluation of a Biomimetic Artificial Photolyase: Repair of Duplex DNA Containing a CPD Photolesion, Andrew T. Johnson, Morgan Underdue, and Olaf Wiest

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Structure and Dynamics of GNA: A Molecular Dynamics Study, Andrew T. Johnson, Olaf Wiest, Lars-Oliver Essen, and Eric Meggers

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ZAK Is Required for Doxorubicin, a Novel Ribotoxic Stressor, to Induce SAPK Activation and Apoptosis in HaCaT Cells, Kristin A. D. Sauter, Eli A. Magun, Mihail S. Iordanov, and Bruce E. Magun

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Internally Mixed Sulfate and Organic Particles as Potential Ice Nuclei in the Tropical Tropopause Region, Matthew E. Wise, Kelly J. Baustian, and Margaret A. Tolbert

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Deliquescence, Efflorescence and Ice Nucleating Ability of NaCl/Hydrated NaCl Particles Under Upper Tropospheric Conditions, M. E. Wise, K. J. Baustian, M. A. Freedman, T. Koop, and M. A. Tolbert

Submissions from 2009

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Depositional Ice Nucleation on Solid Ammonium Sulfate and Glutaric Acid Particles, K. J. Baustian, M. E. Wise, and M. A. Tolbert

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Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis, Erin G. Harper, Changsheng Guo, Heather Rizzo, Joseph V. Lillis, Stephen E. Kurtz, Iliyana Skorcheva, David Purdy, Erin Fitch, Mihail Iordanov, and Andrew Blauvelt

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Hygroscopic Behavior and Liquid-Layer Composition of Aerosol Particles Generated from Natural and Artificial Seawater, Matthew E. Wise, Evelyn J. Freney, Corey A. Tyree, Jonathan O. Allen, Scot T. Martin, Lynn M. Russell, and Peter R. Buseck

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Laboratory Studies of Ice Formation Pathways from Ammonium Sulfate Particles, M. E. Wise, K. J. Baustian, and M. A. Tolbert

Submissions from 2008

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Water Uptake by NaCl Particles Prior to Deliquescence and a Modified Phase Rule, Matthew E. Wise, Scot T. Martin, Lynn M. Russell, and Peter R. Buseck

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Laboratory Studies of Ice Formation Pathways from Ammonium Sulfate Particles, M. E. Wise, K. J. Baustian, and M. A. Tolbert

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Laboratory Studies of Ice Formation Pathways from Ammonium Sulfate Particles, M. E. Wise, K. J. Baustian, and M. A. Tolbert

Submissions from 2007

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Fas Ligand-Induced Proinflammatory Transcriptional Responses in Reconstructed Human Epidermis, Sherry M. Farley, David E. Purdy, Olga P. Ryabinina, Pascal Schneider, Bruce E. Magun, and Mihail S. Iordanov

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The 2.2 Å Resolution Crystal Structure of Bacillus Cereus Nif3-Family Protein YqfO Reveals a Conserved Dimetal-Binding Motif and a Regulatory Domain, Michael H. Godsey, George Minasov, Ludmill Shuvalova, Joseph S. Brunzelle, Ivan I. Vorontsov, Frank R. Collart, and Wayne F. Anderson

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Structure and Dynamics of Poly(T) Single-Strand DNA: Implications toward CPD Formation, Andrew T. Johnson and Olaf Wiest

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Role of Apoptotic Signaling Pathways in Regulation of Inflammatory Responses to Ricin in Primary Murine Macrophages, Veselina Korcheva, John Wong, Meghan Lindauer, David B. Jacoby, Mihail S. Iordanov, and Bruce Magun

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Hygroscopic Behavior of Aerosol Particles from Biomass Fires Using Environmental Transmission Electron Microscopy, Trudi A. Semeniuk, Matthew E. Wise, Scot T. Martin, Lynn M. Russell, and Peter R. Buseck

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Water Uptake Characteristics of Individual Atmospheric Particles Having Coatings, Trudi A. Semeniuk, Matthew E. Wise, Scot T. Martin, Lynn M. Russell, and Peter R. Buseck

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Phase Transitions of Single Salt Particles Studied Using a Transmission Electron Microscope with an Environmental Cell, Matthew E. Wise, George Biskos, Scot T. Martin, Lynn M. Russell, and Peter R. Buseck

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Hygroscopic Behavior of NaCl-Bearing Natural Aerosol Particles Using Environmental Transmission Electron Microscopy, Matthew E. Wise, Trudi A. Semeniuk, Roelof Bruintjes, Scot T. Martin, Lynn M. Russell, and Peter R. Buseck

Submissions from 2006

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Fas Ligand Elicits a Caspase-Independent Proinflammatory Response in Human Keratinocytes: Implications for Dermatitis, Sherry M. Farley, Anjali D. Dotson, David E. Purdy, Aaron J. Sundholm, Pascal Schneider, Bruce E. Magun, and Mihail S. Iordanov

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Structural Basis for the Preference of UTP over ATP in Human Deoxycytidine Kinase:  Illuminating the Role of Main-Chain Reorganization, Michael H. Godsey, Stephen Ort, Elisabetta Sabini, Manfred Konrad, and Arnon Lavie

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D-MEKK1, the Drosophila Orthologue of Mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 Mediate the Activation of D-JNK by Cadmium and Arsenite in Schneider Cells, Olga P. Ryabinina, Ezhilkani Subbian, and Mihail S. Iordanov

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c-Jun NH2-terminal Kinase Promotes Apoptosis by Down-Regulating the Transcriptional Co-repressor CtBP, Su-Yan Wang, Mihail Iordanov, and Qinghong Zhang

Submissions from 2005

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Impact of Palmitic Acid Coating on the Water Uptake and Loss of Ammonium Sulfate Particles, R. M. Garland, M. E. Wise, M. R. Beaver, H. L. DeWitt, A. C. Aiken, J. L. Jimenez, and M. A. Tolbert

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Cell Death-Induced Activation of Epidermal Growth Factor Receptor in Keratinocytes: Implications for Restricting Epidermal Damage in Dermatitis, Mihail S. Iordanov, Aaron J. Sundholm, Eric L. Simpson, Jon M. Hanifin, Olga P. Ryabinina, Remy J. Choi, Veselina B. Korcheva, Pascal Schneider, and Bruce E. Magun

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Recruitment of TRADD, FADD, and Caspase 8 to Double-Stranded RNA-Triggered Death Inducing Dignaling Vomplexes (dsRNA-DISCs), M. S. Iordanov, J. D. Kirsch, O. P. Ryabinina, J. Wong, P. N. Spitz, V. B. Korcheva, A. Thorburn, and B. E. Magun

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Two Mechanisms of Caspase 9 Processing in Double-Stranded RNA- and Virus-Triggered Apoptosis, M. S. Iordanov, O. P. Ryabinina, P. Schneider, and B. E. Magun

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Ozonolysis of Mixed Oleic-Acid/Stearic-Acid Particles:  Reaction Kinetics and Chemical Morphology, Y. Katrib, G. Biskos, P. R. Buseck, P. Davidovits, J. T. Jayne, M. Mochida, M. E. Wise, D. R. Worsnop, and S. T. Martin

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Administration of Ricin Induces a Severe Inflammatory Response via Nonredundant Stimulation of ERK, JNK, and P38 MAPK and Provides a Mouse Model of Hemolytic Uremic Syndrome, Veselina Korcheva, John Wong, Christopher Corless, Mihail Iordanov, and Bruce Magun

Submissions from 2004

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Chronic Liver Disease in Murine Hereditary Tyrosinemia Type 1 Induces Resistance to Cell Death, Arndt Vogel, Inge E. T. van den Berg, Muhsen Al-Dhalimy, John Groopman, Ching-Nan Ou, Olga Ryabinina, Mihail S. Iordanov, Milton Finegold, and Markus Grompe

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Ice Nucleation in Internally Mixed Ammonium Sulfate/Dicarboxylic Acid Particles, Matthew E. Wise, Rebecca M. Garland, and Margaret A. Tolbert

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Deliquescence Investigated by Environmental Transmission Electron Microscopy, M. E. Wise, G. Biskos, S. T. Martin, and P. R. Buseck

Submissions from 2003

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Phase Changes in Internally Mixed Maleic Acid/Ammonium Sulfate Aerosols, Sarah D. Brooks, Rebecca M. Garland, Matthew E. Wise, Anthony J. Prenni, Melinda Cushing, Erika Hewitt, and Margaret A. Tolbert

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Solubility and Freezing Effects of Fe2+ and Mg2+ in H2SO4 Solutions Representative of Upper Tropospheric and Lower Stratospheric Sulfate Particles, Matthew E. Wise, Sarah D. Brooks, Rebecca M. Garland, Daniel J. Cziczo, Scot T. Martin, and Margaret A. Tolbert

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Hygroscopic Growth of Ammonium Sulfate/Dicarboxylic Acids, Matthew E. Wise, Jason D. Surratt, Daniel B. Curtis, John E. Shilling, and Margaret A. Tolbert

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Ice Nucleation in Internally Mixed Ammonium Sulfate/Dicarboxylic Acid Particles, M. E. Wise, R. M. Garland, and M. A. Tolbert

Submissions from 2002

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Deliquescence Behavior of Organic/Ammonium Sulfate Aerosol, Sarah D. Brooks, Matthew E. Wise, Melinda Cushing, and Margaret A. Tolbert

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Structural Biology of Bacterial Multidrug Resistance Gene Regulators, Michael H. Godsey, Ekaterina E. Zheleznova Heldwein, and Richard G. Brennan

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The UV (Ribotoxic) Stress Response of Human Keratinocytes Involves the Unexpected Uncoupling of the Ras-Extracellular Signal-Regulated Kinase Signaling Cascade from the Activated Epidermal Growth Factor Receptor, Mihail S. Iordanov, Remy J. Choi, Olga P. Ryabinina, Thanh-Hoai Dinh, Robert K. Bright, and Bruce E. Magun

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Solubility and Freezing Effects of Fe2+ and Mg2+ in H2SO4 Solutions at Upper Tropospheric and Lower Stratospheric Temperatures and Compositions, M. E. Wise, S. D. Brooks, R. M. Garland, D. J. Cziczo, D. M. Murphy, S. T. Martin, and M. A. Tolbert

Submissions from 2001

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Crystal Structure of MtaN, a Global Multidrug Transporter Gene Activator, Michael H. Godsey, Natalya N. Baranova, Alexander A. Neyfakh, and Richard G. Brennan

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Activation of NF-κB by Double-Stranded RNA (dsRNA) in the Absence of Protein Kinase R and RNase L Demonstrates the Existence of Two Separate dsRNA-Triggered Antiviral Programs, Mihail S. Iordanov, John Wong, John C. Bell, and Bruce E. Magun

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Specifically Targeting the CD22 Receptor of Human B-cell Lymphomas with RNA Damaging Agents, Dianne L. Newton, Hans J. Hansen, Huaitian Liu, Dale Ruby, Mihail S. Iordanov, Bruce E. Magun, David M. Goldenberg, and Susanna M. Rybak

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Ice Nucleation in Sulfuric Acid and Ammonium Sulfate Particles, Anthony J. Prenni, Matthew E. Wise, Sarah D. Brooks, and Margaret A. Tolbert

Submissions from 2000

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Crystallization and Preliminary X-ray Diffraction Studies on the DNA-Binding Domain of the Multidrug Transporter Activation Protein (MtaN) from Bacillus subtilis, M. H. Godsey, N. N. Baranova, A. A. Neyfakh, and R. G. Brennan

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Activation of p38 Mitogen-Activated Protein Kinase and c-Jun NH2-Terminal Kinase by Double-Stranded RNA and Encephalomyocarditis Virus: Involvement of RNase L, Protein Kinase R, and Alternative Pathways, Mihail S. Iordanov, Jayashree M. Paranjape, Aimin Zhou, John Wong, Bryan R. G. Williams, Eliane F. Meurs, Robert H. Silverman, and Bruce E. Magun

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Molecular Determinants of Apoptosis Induced by the Cytotoxic Ribonuclease Onconase: Evidence for Cytotoxic Mechanisms Different from Inhibition of Protein Synthesis, Mihail S. Iordanov, Olga P. Ryabinina, John Wong, Thanh-Hoai Dinh, Dianne L. Newton, Susanna M. Rybak, and Bruce E. Magun

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Differential Requirement for the Stress-Activated Protein Kinase/c-Jun NH2-Terminal Kinase in RNA Damage-Induced Apoptosis in Primary and in Immortalized Fibroblasts, Mihail S. Iordanov, John Wong, Dianne L. Newton, Susanna M. Rybak, Robert K. Bright, Richard A. Flavell, Roger J. Davis, and Bruce E. Magun

Ice Nucleation and Solubility Studies of Sulfates Representative of the Upper Tropospheric Aerosol, M. E. Wise, A. J. Prenni, S. D. Brooks, D. J. Cziczo, D. M. Murphy, and M. A. Tolbert

Submissions from 1999

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Different Mechanisms of c-Jun NH2-terminal Kinase-1 (JNK1) Activation by Ultraviolet-B Radiation and by Oxidative Stressors, Mihail S. Iordanov and Bruce E. Magun

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The p38MAPK Inhibitor SB203580 Alleviates Ultraviolet-Induced Phosphorylation at Serine 389 but Not Serine 15 and Activation of p53, David Keller, Xiaoya Zeng, Xiaorong Li, Mini Kapoor, Mihail S. Iordanov, Yoichi Taya, Guillermina Lozano, Bruce Magun, and Hua Lu

Submissions from 1998

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Loss of Cellular K+ Mimics Ribotoxic Stress, Mihail S. Iordanov and Bruce E. Magun

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Ultraviolet Radiation Triggers the Ribotoxic Stress Response in Mammalian Cells, Mihail S. Iordanov, David Pribnow, Jennifer L. Magun, Thanh-Hoai Dinh, Jean A. Pearson, and Bruce E. Magun

Submissions from 1997

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UV-Induced Signal Transduction, Klaus Bender, Christine Blattner, Axel Knebel, Mihail Iordanov, Peter Herrlich, and Hans J. Rahmsdorf

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CREB is Activated by UVC Through a p38/HOG-1-Dependent Protein Kinase, M. Iordanov, K. Bender, T. Ade, W. Schmid, C. Sachsenmaier, K. Engel, M. Gaestel, H. J. Rahmsdorf, and P. Herrlich

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Ribotoxic Stress Response: Activation of the Stress-Activated Protein Kinase JNK1 by Inhibitors of the Peptidyl Transferase Reaction and by Sequence-Specific RNA Damage to the Alpha-Sarcin/Ricin Loop in the 28S rRNA, Mihail S. Iordanov, David Pribnow, Jennifer L. Magun, Thanh-Hoai Dinh, Jean A. Pearson, Steven Li-Ye Chen, and Bruce E. Magun

Probing Surface Reaction Mechanism Using In-Situ FTIR Spectroscopy: NO and CO Reaction on a Platinum Surface, M. E. Wise, N. P. Magtoto, and H. H. Richardson

Submissions from 1996

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An Oxidant Sensor at the Plasma Membrane, Alex Knebel, Mihail Iordanov, Hans J. Rahmsdorf, and Peter Herrlich